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NABP NAPLEX Exam Questions
- Topic 1: Assess Pharmacotherapy to Assure Safe and Effective Therapeutic Outcomes: This section measures the skills of Pharmacy Candidates and covers the evaluation of pharmacotherapy to ensure safe and effective therapeutic outcomes. Candidates will learn to assess patient data, develop treatment plans, and manage medication therapy. This area constitutes a significant portion of the exam, emphasizing the importance of understanding drug interactions, therapeutic goals, and clinical endpoints.
- Topic 2: Assess Safe and Accurate Preparation and Dispensing of Medications: In this section, the exam focuses on Pharmacists and addresses the safe and accurate preparation and dispensing of medications. Candidates will explore the principles of compounding, dispensing practices, and quality assurance measures.
- Topic 3: Assess, Recommend, and Provide Health Care Information that Promotes Public Health: Targeted at Pharmacists, this section covers the role of pharmacists in promoting public health through Education and information dissemination.
- Topic 4: Perform Calculations: This section is aimed at Pharmacy Technicians and focuses on performing essential calculations related to pharmacy practice.
- Topic 5: Compounding, Dispensing, Administering, and Delivery Systems: This section measures the skills of Clinical Pharmacists and examines the processes involved in compounding, dispensing, administering medications, and utilizing delivery systems.
- Topic 6: Safety and Quality of Medical-Use Systems: In this final section, this domain focuses on Quality Assurance Specialists and addresses safety measures within medical-use systems. Candidates will learn about risk management strategies, error prevention techniques, and quality control processes essential for maintaining high standards in pharmacy practice.
Free NABP NAPLEX Exam Actual Questions
Note: Premium Questions for NAPLEX were last updated On May. 07, 2025 (see below)
LN is 84 YOM who is in hospital for a back surgery. His height is 5 feet and 4 inches, weight 85 kg and NKDA.
His past medical history includes hypertension, diabetes mellitus, major depression, hypothyroidism and chronic back pain. Post-op day 1, LN's medication includes Dexamethasone 8mg iv q6h with taper dosing, Ondansetron 4mg iv q6h prn for N/V, Levothyroxine 0.075mg po daily, Lisinopril 10mg po daily, Citalopram 20mg po daily, Docusate sodium / Senna 1 tab po twice a day, Bisacodyl 10mg suppository daily prn for constipation, Famotidine 20mg iv q12hr, Metoclopramide 10mg iv q6h, Metformin 500mg po bid, D51/2NS with 20K at 125mls/hour and Hydromorphone PCA at 0.2mg/hour of basal rate, demand dose 0.1mg. lock-out
every 6min, one hour limit 2.2mg/hour. Pertinent morning labs includes serum creatinine 1.4mg/dl, Mg 1.5mg/ dl, K 5.0mmol/L, Na 135mmol/L. The bioavailability of levothyroxine is roughly 50%.
The physician requests you for a dose recommendation to convert her home dose of 75mcg po daily to intravenous.
What would be the appropriate intravenous dose?
Since the bioavailability of levothyroxine is roughly 50% (given in the Question:). To convert
the home dose to intravenous, it would be 50% of the oral dose. So 50% of oral 75 mcg would be 37.5 mcg intravenously.
Select the class of Anti-diabetic medication that works in the specified organ to prevent hyperglycemi
a. Select all that applies. Liver (D)
DPP4 Inhibitors, (D)Glucagon-like peptide-1 receptor agonists, (E)Thiazolidinediones (F)Biguanide Sulfonylureas work in beta cells in the pancreas that are still functioning to enhance insulin secretion. Alpha- Glucosidase Inhibitors stop -glucosidase enzymes in the small intestine and delay digestion and absorption of starch and disaccharides which lowers the levels of glucose after meals. DPP4 blocks the degradation ofGLP-1, GIP, and a variety of other peptides, including brain natriuretic peptide. Glucagon-like peptide-1 receptor agonists work in various organs of the body. Glucagon-like peptide-1 receptor agonists enhance glucose homeostasis through: (i) stimulation of insulin secretion; (ii) inhibition of glucagon secretion; (iii) direct and indirect suppression of endogenous glucose production; (iv) suppression of appetite; (v) enhanced insulin sensitivity secondary to weight loss; (vi) delayed gastric emptying, resulting in decreased postprandial hyperglycaemia. Thiazolidinediones are the only true insulin-sensitising agents, exerting their effects in skeletal and cardiac muscle, liver, and adipose tissue. It ameliorates insulin resistance, decreases visceral fat.
Biguanides work in liver, muscle, adipose tissue via activation of AMP-activated protein kinase (AMPK) reduce hepatic glucose production. SGLT2 inhibitors work in the kidneys to inhibit sodium-glucose transport proteins to reabsorb glucose into the blood from muscle cells; overall this helps to improve insulin release from the beta cells of the pancreas.
https://doi.org/10.1093/eurheartj/ehv239
An order is received for 0.03 units /min of vasopressin for Sepsis to maintain MAP >65. The standard mixed in your hospital for vasopressin is 40 units in 100ml NS.
What is the rate in mLs/hr should the vasopressin be infused at?
Rate of infusion: 100mL/40U 0.03U/min 60min/1 hr = 4.5mL/hr
Which of the following is dichotomous variable?
Dichotomous data is considered categorical data that only has two categories, or two answer choices. All 3 answer choices have only 2 categories: sex has male or female, pain is yes or no, and alive or dead is only two options also.
http://www.bmj.com/about-bmj/resources-readers/publications/statistics-square-one
Mesna is typically administered alongside which of these chemotherapeutic agents?
Mesna is administered to patients taking either ifosfamide or cyclophoshamide to conjugate toxic acrolein and therefore prevent hemorrhagic cystitis (bladder bleeding).
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