NABP Exam FPGEE Topic 6 Question 94 Discussion

Actual exam question for NABP's FPGEE exam

Question #: 94
Topic #: 6

In an adequately powered, randomized controlled trial conducted over 2 years, the desired clinical outcome (i.e. prevention of a serious cardiovascular event) with a new drug is achieved in 25% of the study sample. In the patients who receive a placebo, only 15% obtain the same clinical benefit. The relative risk reduction achieved with the new drug over the study period is:

A10%.

B15%.

C25%.

D40%.

E50%.

Show Suggested Answer

Suggested Answer: B

by Kiley at Sep 13, 2024, 06:31 PM

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Tambra

1 months ago

Ugh, I knew this one would be tricky. At least I can eliminate the wrong answers and narrow it down. Relative risk reduction, not absolute risk - got it, thanks Yuonne!

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Altha

1 months ago

I was going to say E) 50%, but now I see my mistake. Relative risk reduction is not the same as absolute risk reduction. Silly me, I should have paid more attention in class.

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Jamal

1 months ago

Definitely D) 40%. I'm glad I reviewed the relative risk reduction concept before the exam. It's a common question type in these kinds of trials.

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Pamella

4 days ago

D) 40%.

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Xenia

8 days ago

C) 25%.

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Skye

18 days ago

B) 15%.

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Deonna

19 days ago

A) 10%.

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Elvis

1 months ago

I was thinking the same, Yuonne. The relative risk reduction formula is straightforward, and the numbers provided make it a simple calculation.

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Denise

10 days ago

C) 25%

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Jaclyn

12 days ago

B) 15%

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Timothy

29 days ago

A) 10%

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Yuonne

2 months ago

I think the answer is D) 40%. The relative risk reduction is the difference in the event rate between the treatment and placebo groups, divided by the event rate in the placebo group. In this case, it's (25% - 15%) / 15% = 0.4 or 40%.

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