NABP Exam FPGEE Topic 2 Question 85 Discussion

Actual exam question for NABP's FPGEE exam

Question #: 85
Topic #: 2

[All FPGEE Questions]

Mechanism of action of doxorubicin is:

AInhibits topoisomerase II

Balpha antagonist

CInhibits peptidyl transferase

Dbeta antagonist

EAllosterically enhances GABAergic inhibition

Show Suggested Answer

Suggested Answer: E

by Marge at Jun 28, 2024, 05:02 PM

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Eun

22 days ago

Wait, doxorubicin is an alpha blocker? That's just ridiculous. I'm going to have to go with the classic topoisomerase II inhibitor, A.

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Belen

5 days ago

I've also heard that doxorubicin works by inhibiting topoisomerase II. It's a well-known mechanism for this drug.

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Marge

11 days ago

Yeah, A is the correct answer. It's a common mechanism of action for doxorubicin.

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Lashandra

15 days ago

I agree, doxorubicin is definitely not an alpha blocker. Topoisomerase II inhibition makes more sense.

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Catarina

25 days ago

Hmm, allosterically enhancing GABA? That's just silly. This is clearly a cancer drug, not a central nervous system one. A has got to be the right answer here.

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Mona

27 days ago

Haha, beta antagonist? What is this, a cardiovascular exam? Definitely not D. I'm going to go with the topoisomerase II option, A.

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Marlon

8 days ago

Yeah, that's right. Doxorubicin works by inhibiting topoisomerase II.

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Kimbery

9 days ago

I think A is correct, it inhibits topoisomerase II.

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Chun

30 days ago

Wait, isn't doxorubicin an antitumor antibiotic? I think it's got to be something related to DNA or protein synthesis. C - inhibits peptidyl transferase seems more plausible.

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Lashandra

1 months ago

Doxorubicin is a chemotherapy drug, so it's got to be inhibiting something important for cancer cells. I'm going with A - inhibits topoisomerase II. Sounds like the right mechanism to me.

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