NABP Exam FPGEE Topic 2 Question 85 Discussion

Actual exam question for NABP's FPGEE exam

Question #: 85
Topic #: 2

[All FPGEE Questions]

Mechanism of action of doxorubicin is:

AInhibits topoisomerase II

Balpha antagonist

CInhibits peptidyl transferase

Dbeta antagonist

EAllosterically enhances GABAergic inhibition

Show Suggested Answer

Suggested Answer: E

by Marge at Jun 28, 2024, 05:02 PM

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Eun

6 days ago

Wait, doxorubicin is an alpha blocker? That's just ridiculous. I'm going to have to go with the classic topoisomerase II inhibitor, A.

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Catarina

9 days ago

Hmm, allosterically enhancing GABA? That's just silly. This is clearly a cancer drug, not a central nervous system one. A has got to be the right answer here.

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Mona

11 days ago

Haha, beta antagonist? What is this, a cardiovascular exam? Definitely not D. I'm going to go with the topoisomerase II option, A.

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Chun

14 days ago

Wait, isn't doxorubicin an antitumor antibiotic? I think it's got to be something related to DNA or protein synthesis. C - inhibits peptidyl transferase seems more plausible.

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Lashandra

25 days ago

Doxorubicin is a chemotherapy drug, so it's got to be inhibiting something important for cancer cells. I'm going with A - inhibits topoisomerase II. Sounds like the right mechanism to me.

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